William E. Wall

“TokensGreen mwold on zummer bars do show That they’ve a-dripp’d in winter wet; The hoof-worn ring o’ groun’ below The tree, do tell o’ storms or het; The trees in rank along a ledge Do show where woonce did bloom a hedge; An’ where the vurrow-marks do stripe The down, the wheat woonce rustled ripe. Each mark ov things a-gone vrom view”

“Like humans, bacteria and fungi live and die. Although their relations don’t conduct funerals for them or erect headstones over their graves, their life cycles, unlike our many decades, are measured in hours to days, reflecting a lightning-fast rate of turnover. With that much life and death cycling in your GI tract, involving trillions of creatures, where do the by-products go upon their death? Without wills or estates to settle, the remains of trillions of microbes are recycled by other microbes, some are metabolized by you, and others are passed out into the toilet. But in dysbiosis, some remnants also invade our bloodstream and thereby are “exported” to other parts of the body. In 2007, a French research group reported on this critical phenomenon. They labeled this flood of toxic bacterial breakdown products “metabolic endotoxemia,” and it has been found to underlie numerous modern health conditions, especially those driven by inflammation, such as type 2 diabetes, heart disease, and neurodegenerative diseases.4 The main driver of endotoxemia is something called lipopolysaccharide, or LPS, which originates in the cell walls of organisms such as Escherichia coli (E. coli) and Klebsiella, common inhabitants of the colon and stool. When those microbes die, their cell wall contents are liberated, and if the integrity of the intestinal wall has been compromised by pathogenic species, the LPS can pass through this broken barrier into the blood. The consequences of endotoxemia are especially powerful when all thirty feet of the GI tract are filled with unhealthy microbes.””