William T. Belfield was a pioneering American urologist, renowned for performing the first intentional prostatectomy via the suprapubic route in the late 1880s at Cook County Hospital. Born in St. Louis, Missouri, and raised in Chicago, Belfield earned his medical degree from Rush Medical College in 1877. He quickly established himself in the field of urology, becoming the chair of the department at his alma mater in 1883. His surgical innovations and techniques laid the groundwork for modern urological practices, significantly advancing the treatment of prostate conditions. In addition to his surgical accomplishments, Belfield played a crucial role in the early development of microbiology in the United States. He was instrumental in reporting Robert Koch's discovery of Mycobacterium tuberculosis, which underscored his commitment to integrating surgical practice with emerging scientific knowledge. His leadership as the sixth president of the American Urological Association further solidified his influence in the medical community. Belfield's contributions to urology and microbiology not only marked significant milestones in medical history but also established standards that would guide future generations of surgeons and researchers.